肿瘤标记物联合多层螺旋CT在早期肺癌患者中诊断价值分析

Diagnostic Value of Tumor Markers Combined with Multi-slice Spiral CT in Patients with Early Lung Cancer

目的探讨肿瘤标记物联合多层螺旋CT诊断早期肺癌的临床价值。方法选择我院2012年3月至2016年3月期间收治的62例肺癌患者作为研究对象,患者均行肿瘤标志物检测及螺旋CT检查,总结SQC、ADC、SCLC等不同类型肺癌的螺旋CT征象特点,分别计算肿瘤标志物诊断肺癌的敏感性及联合诊断的敏感性。结果 SQC的Cyfra21-1诊断符合率最高,为71.4%(20/28);ADC的CEA诊断符合率最高,为70.8%(17/24);SCLC的NSE诊断符合率最高,为70.0%(7/10)。肿瘤标记物联合诊断肺癌的符合率为80.6%(50/62),肿瘤标志物与螺旋CT联合诊断肺癌的符合率为93.5%(58/62),差异有统计学意义(χ~2=4.5 9 3,P=0.032)。结论肿瘤标记物联合多层螺旋CT诊断早期肺癌具有更高诊断符合率,具有良好临床应用价值。

Objective To investigate the clinical value of tumor marker combined with multi-slice spiral CT in the diagnosis of early hmg cancer. Methods Sixty-two patients with lung cancer admitted to our hospital between March 2012 and March 2016 were selected as the study subjects. The tumor marker detection and spiral CT examination were performed. The spiral CT features of SQC, ADC, SCLC and other types of hmg cancer were summarized. The sensitivities of tumor markers and the combined diagnosis of lung cancer were calculated respectively. Results The coincidence rate of Cyfra 21-1 in the diagnosis of SQC was the highest, which was 71.4% （20/28）. The coincidence rate of CEA in the diagnosis of ADC was the highest, which was 70.8% （17/24）; The coincidence rate of NSE in the diagnosis of SCLC was the highest, which was 70% （7/10）. The coincidence rate of combined diagnosis of tumor markers was 80.6% （50/62） while the coincidence rate of tumor markers combined with spiral CT in the diagnosis of lung cancer was 93.5% （58/62） （X^2=4.593, P=0.032）. Conclusion The coincidence rate of tumor markers combined with multi-slice spiral CT in the diagnosis of early lung cancer is high, with high clinical application value.