24h多通道食管阻抗-pH监测在鉴别非糜烂性反流病和功能性烧心中的作用

The Role of 24h Multichannel Esophageal Impedance-pH Monitoring in the Identification of Non Erosive Reflux Disease and Functional Burn

目的探究多通道食管阻抗监测于非糜烂性反流病与功能性烧心上的临床鉴别价值。方法择取2015年1月~2016年6月由笔者所在医院收治的98例非糜烂性反流病患者(内镜检查均为阴性),设为研究组;再择取同期收治的98例健康受检者,设为对照组。为两组患者全部实行多通道食管阻抗监测,探究食管酸的暴露时间以及各反流事件的发生概率。结果按照监测结果分组:A组:阳性,39例(39.80%);B组:阴性/阳性,37例(37.76%);C组:阴性/阴性组,22例(22.45%)。A组在总返流次数、液体反流次数、酸反流次数、上明显高于B组、C组与对照组;B组在上述指标上高于C组和对照组。C组与对照组则无统计学差异(P>0.05)。结论临床可以通过多通道食管阻抗监测鉴别出与,其临床诊断价值鲜明。

Objective To explore 24 h multichannel esophageal impedance monitoring-pH non-erosive reflux disease and the clinical differential diagnosis of functional heartburn on.Methods Choose to take the January 2015 to June 2016 period by the author of the hospital admitted 66 patients with non-erosive reflux disease（endoscopy were negative）,to study groups; then choose to take the year admitted 66 healthy subjects,as control group.Full implementation of the two groups of patients with multi-channel 24 h esophageal impedance monitoring-pH,explore the probability of occurrence of esophageal acid exposure time ？as well as the reflux events.Results The monitoring results 66 patients were divided into three study groups Group：（1）pH positive group（A）,39 cases（39.80%）;（2）pH negative/SAP-positive group（group B）,37 cases（37.76%）;（3）pH negative/SAP-negative group（group C）,22 cases（22.45%）. A group in the total number of reflux liquid reflux episodes,the number of acid reflux,the AET significantly higher than group B,group C and control group; group B in the index was significantly higher than group C and control group.No significant difference（P〉0.05） in group C and control groups was none.Conclusion Clinical can 24 h multichannel esophageal impedance monitoring-pH clearly identify non-erosive reflux disease heartburn on functionality,its diagnostic value clear.