改善睡眠药物在冠心病合并失眠中的疗效观察

The role of sleep improving medicine in the treatment of coronary heart disease with insomnia

目的:观察改善睡眠药物在冠心病合并失眠中的治疗效果。方法:收集2014年3月~2016年3月所有住院期间临床诊断的冠心病、且治疗后症状无明显改善并有失眠的患者,按照时间分为实验组及对照组,两组分别予以镇静催眠药物及强化冠心病药物治疗,观察两组症状改善情况及住院时间。结果:实验组较对照组,治疗72h后睡眠质量显著改善(分别为73.63%和22.99%,P<0.05),实验组在不增加药物的情况下症状明显改善(67.03%和40.23%,P<0.05),显著高于对照组;两组平均住院时间为(11.93±2.67)d和(13.26±2.13)d,P<0.05。结论:改善睡眠可明显改善冠心病合并失眠临床症状,缩短住院时间。

Objective：To evaluate the effect of sleep improving medicine in the treatment of coronary heart disease patients （CHD） with insomnia. Method：All the patients diagnosed of CHD with insomnia and without obvious symptoms improved after 72 hours of inpatient treatment around 2014 March to 2016 March were collected and divided into experimental group and control group in chronological order, two groups were given a sedative and hypnotic drug and enhanced coronary drug treatment respectively. Symptoms improvment after enrollment of 72 hours and hospitalization duration were observed in two group patients. Result： Sleep were significantly improved in experimental group than control group （73.63%and22.99%,respectively,P〈0.05）, and experiment group get less average stay and better treatment effect without more medicine. The average stay was （11.93±2.67）d and （13.26±2.13）d in experiment group and control group, respectively, P〈0.05; and 67.03% and 40.23% of symptom improved after 72 hour＇s of enrollment （P〈0.05）. Conclusion：Improving sleep can significantly improve the clinical symptoms in patients with coronary heart disease, shorten the hospitalization time.