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分析比较硝苯地平缓释片和非洛地平缓释片的降压疗效

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摘要 目的:分析比较硝苯地平缓释片和非洛地平缓释片的降压疗效。方法:将我院100例符合1999年WHO/ISH诊断标准的门诊原发性高血压患者随机平分为两组:硝苯地平组50例,非洛地平组50例,用药4周为一个疗程,比较治疗前后的血压。结果:非洛地平组的治疗总有效率为96.0%略高于硝苯地平组94.0%,治疗后的SBP、DBP水平略低于硝苯地平组。结论:经过4周治疗,治疗效果比较:在疗程观察期内血压下降平稳持久,能够24h维持在有效血药浓度,没有出现"延迟释放"造成的血压骤升,也没有出现"突释"现象所致的面红耳赤、头痛、头晕、心率加快等副反应,非洛地平和硝苯地平缓释片作为长效、高选择性的CCB类降压药,降压效果更明显,更持久,更稳定,是比较理想的降压药。
出处 《北方药学》 2017年第5期64-64,共1页 Journal of North Pharmacy
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