盐田辖区上呼吸道感染耐药情况分析

Analysis on drug resistance of respiratory tract infection situation of Yantian District

目的:研究我院辖区居民细菌性上呼吸道感染的病原菌分布及其对抗生素的敏感性,让辖区内科同仁使用抗生素时参考。方法:选择2014年6月~2016年11月使用经验抗生素治疗细菌性上感231例进行咽拭子培养,其中200例阳性标本进行细菌鉴定及药敏培养,统计细菌培养阳性比例、细菌种类,对比经验治疗中,使用了敏感抗生素的比例、使用了耐药抗生素的比例。结果:上呼吸道感染细菌培养阳性率为86.5%,感染的病原菌中以革兰阴性杆菌为主,占73.5%,其次为格兰氏阳性球菌,占24.5%。病原菌对常用药中的头孢噻肟、头孢哌酮较为敏感,对青霉素、红霉素、克林霉素较不敏感。200例经验抗生素治疗符合敏感的153例,占76.5%,不敏感的47例,占23.5%。结论:辖区细菌性上呼吸道感染的经验抗生素治疗中,有少部分与细菌培养不一致,本次研究可作为区域选择抗菌药物时参考。

Objective： To study the distribution of pathogenic bacteria and their sensitivity to antibiotics in our hospital. Methods ：June 2014 to November 2016 experience in the use of antibiotics in the treatment of bacterial upper respiratory tract infection in 231 cases of pharyngeal swab culture, 200 of which were positive specimens for bacteria identification and drug sensitivity training, statistical bacterial culture positive rate of bacterial species, comparing treatment experience, use ratio, use of sensitive antibiotics resistant to antibiotics. Results： the positive rate of bacterial culture in upper respiratory tract infection was 86.5%, and the main pathogens were gram-negative bacilli, accounting for 73.5%, followed by Galanz positive bacteria, accounting for 24.5%. The pathogen of commonly used drugs in cefotaxime, cefoperazone is sensitive to penicillin, erythromycin and clindamycin are less sensitive. Experience antibiotic treatment in 200 cases of 153 cases, accounting for 76.5%, 47 eases were not sensitive, accounting for 23.5%. Conclusion： in the area of bacterial upper respiratory tract infection, there is a small part of antibiotic treatment. The study can be used as a reference for the selection of antimicrobial agents in the area.