声触诊组织成像鉴别临床不易触诊乳腺小结节的应用价值

The application value of virtual touch tissue imaging in differential diagnosis of clinical cannot palpation to small breast nodules

目的探讨声触诊组织成像(virtual touch tissue imaging,VTI)在临床不易触诊乳腺小结节良恶性鉴别诊断中的应用价值。方法应用VTI技术分析经病理证实的82例患者98个直径≤1 cm的乳腺小结节图像特征。通过对乳腺结节硬度分级,计算结节VTI图像与灰阶图像面积比。绘制ROC曲线,找出面积比诊断恶性小结节的最佳截点。结果乳腺结节恶性组Ⅳ级以上的出现率明显高于良性组(P<0.01)。乳腺恶性结节的VTI面积比大于良性结节[(2.14±0.39)vs(1.40±0.20),P<0.001],以面积比1.71为截点诊断临床不易触诊乳腺恶性结节敏感性、特异性分别为95.1%、98.2%。结论 VTI技术可提供乳腺结节硬度信息,对临床不易触诊乳腺小结节的鉴别诊断具有较高的应用价值。

Objective To investigate the application value of virtual touch tissue imaging（VTI）in the differential diagnosis of benign and malignant breast nodules in clinical cannot palpation.Methods VTI technique was used to analyze the characteristics of 98 small breast nodules of 82 patients with pathologically proved breast nodules,which the diameter was less than 1 cm.The classification of breast nodule hardness was used to calculate VTI images to gray scale image area ratio.To draw the ROC curve and find out the best cut-off point of the diagnosis of malignant nodules.Results The incidence rate of grade IV or V in malignant group was significantly higher than that in benign group（P〈0.01）.VTI area ratio of breast malignant nodules was larger than that of benign nodules [（2.14±0.39）vs（1.40±0.20）,P〈0.001].The sensitivity and specificity of the diagnosis of breast malignant nodules were 95.1% and 98.2% respectively,with the area ratio of 1.71 as the cut-off point.Conclusion VTI technology can provide the information of the hardness of breast nodules,and has a high value of application in the differential diagnosis of small breast nodules in clinical cannot palpation.