不同RRF状态持续性非卧床式腹膜透析患者的临床指标、生活质量及其相关因素分析

Clinical indicators, quality of life and related factors in patients with persistent ambulatory peritoneal dialysis with different RRF status

目的探讨不同RRF状态持续性非卧床式腹膜透析患者的临床指标、生活质量及其相关因素。方法选取2014年7月~2016年7月我院接收的88例长期腹膜透析患者,根据患者r GFR情况分成RRF组47例和无RRF组41例,记录所有患者各项临床资料以及生活质量评分等情况,进行分析比较。结果两组患者在年龄、性别、原发病类型、体重指数、收缩压、舒张压、胆固醇、甘油三酯、高密度脂蛋白以及低密度脂蛋白等方面无明显差异(P>0.05);而在冠心病例数、腹膜透析时间、血红蛋白、血清白蛋白、血肌酐、血钾、血钙、血磷以及C反应蛋白含量方面有显著差异(P<0.05)。RRF组患者SF-36总分平均(59.50±16.82)分,显著高于无RRF组患者的(50.84±18.73)分,两组比较差异有统计学意义(P<0.05)。腹膜透析时间、血肌酐、血钙、血钾、血鳞及C反应蛋白水平与腹膜透析患者生活质量呈负相关(P<0.05);血红蛋白、血清白蛋白水平与腹膜透析患者生活质量呈正相关。结论保留RRF的持续性非卧床腹膜透析患者生活质量更高,腹膜透析时间、营养状况、微炎症状态等因素与患者生活质量具有相关性。

Objective To investigate the clinical outcome, quality of life and its related factors in patients with persistent ambulatory peritoneal dialysis with different RRF status. Methods From July 2014 to July 2016 in our hospital 88 patients receiving long-term peritoneal dialysis patients, according to the rGFR patients were divided into RRF group （47 cases） and non RRF group （41 cases）, all patients recorded the clinical data and the quality of life score, analysis and comparison. Results The age, gender, type of primary disease, body mass index, systolic blood pressure, diastolic blood pressure, cholesterol, triglyceride, high density lipoproteiu, low density lipoprotein of the two groups had no significant difference（P〉0.05）; the reaction in coronary heart disease cases, peritoneal dialysis time, hemoglobin, serum albumin, serum creatinine, serum potassium, serum calcium, phosphorus and C reactive protein of the two groups were significant differences（P〈0.05）. The total score of SF-36 in the patients RRF group was（59.50±16.82） points, which was significantly higher than that in the patients without RRF, with an average of （50.84±18.73） points, and ＇the difference between the two groups were statistically significant （P〈0.05）. The level of peritoneal dialysis time, serum creatinine, serum calcium, serum potassium level, phosphorus and C reactive protein and the quality of life in paiients with peritoneal dialysis were negatively correlated （P〈0,05）; hemoglobin, serum albumin were associated with quality of life in patients with peritoneal dialysis positive relationship （P〈0.05）. Conclusion The quality of life of patients with continuous ambulatory peritoneal dialysis （RRF） remained high, the peritoneal dialysis time, nutritional status, micro inflammatory state and other factors were related withthe quality of life.