经导管介入治疗动脉导管未闭临床分析

Clinical analysis of transcatheter interventional therapy for patent ductus arteriosus

目的评价经导管介入封堵治疗动脉导管未闭的安全性及疗效。方法收集我院2010年12月~2014年12月收治的52例动脉导管未闭患者,其中男20例,女32例,年龄1~46岁;在影像学引导下应用封堵器行导管封堵术治疗动脉导管未闭,所有患者在术前、术后1 d行心电图(ECG)、胸片和经胸超声心动图(TTE)检查,术后1、3、6、12个月、2年进行随访。结果 52例患者中50例手术成功,术后为患者行心脏超声检查左右心腔缩小,肺动脉压降低,术后患者的心功能得到改善。结论经导管封堵治疗动脉导管未闭具有操作简便、安全、技术成功率高等优点,是一种安全有效的治疗方法。

Objective To evaluate the safety and efficacy of transcatheter interventional occlusion treatment for patent ductus arteriosus. Methods Fifty-two patients with patent duetus arteriosus including 20 males and 32 females, aged 1-46 years in our hospital from December 2010 to December 2014 were enrolled. The patients were treated with tran-scatheter interventional occlusion treatment for patent ductus arteriosus by occlusion instrument under the guidance of imaging. The electrocardiogram（ECG）, chest radiograph and transthoracic echocardiography（TTE） in all patients were performed before surgery and at 1 day after surgery. And the patients were followed up at 1, 3, 6, 12 months and 2 years after operation. Results Among 52 patients, 50 cases were successfully operated. After surgery, cardiac ultrasonography were performed in patients and showed that the left and right ventricular tachycardia were reduced and the pulmonary artery pressure was decreased. It also showed that the cardiac function of the patients was improved. Conclusion Tran-scatheter closure of patent ductus arteriosus has the advantages of simple operation, safety and high technological success rate. It is a safe and effective treatment method.