摘要
目的:观察微创针刀镜联合常规药物治疗难治性痛风急性期的临床疗效。方法:将62例难治性痛风急性期患者随机分为对照组30例和治疗组32例。对照组采用常规药物(秋水仙碱、碳酸氢钠、塞来昔布、别嘌呤醇等)治疗,治疗组在对照组基础上加用微创针刀镜治疗。2组均以14 d为1个疗程。观察2组临床疗效及治疗前后血尿酸、关节疼痛消失时间及主要临床症状(关节疼痛、肿胀、活动受限)积分。结果:治疗组临床治愈18例,显效6例,有效7例,无效1例,总有效率为96.88%;对照组临床治愈15例,显效5例,有效3例,无效7例,总有效率为76.67%。2组比较,差异有统计学意义(P<0.05)。治疗后,2组血尿酸、关节疼痛消失时间、主要临床症状(关节疼痛、肿胀、活动受限)积分较治疗前均显著下降(P<0.01),且治疗组优于对照组(P<0.05或P<0.01)。结论:微创针刀镜联合常规药物治疗难治性痛风急性期效果显著。
Objective:To observe the clinical efficacy of needlescope combined with conventional medicine in the treatment of acute stage of intractable gout.Methods:Sixty two patients with acute phase of intractable gout were randomly divided into a control group ( 30 cases ) and a treatment group ( 32 cases ) . The control group was treated with conventional drugs ( colchicine,sodium bicarbonate,celecoxib,allopurinol, etc. ) ,and the treatment group,based on the treatment for the control group,was treated with needlescope.Both groups were treated for 14 days as a course of treatment.The clinical efficacy, serum uric acid before and after treatment,the disappearance time of joint pain,and scores of main clinical symptoms (joint pain,swelling and limitation of activity ) were observed in the two groups.Results:In the treatment group,18 cases were cured, 6 cases were markedly effective,7 cases were effective,and 1 case was ineffective,and the total effective rate was 96.88%.In the control group,15 cases were cured,5 cases were markedly effective,3 cases were effective,and 7 cases were ineffective,and the total effective rate was 76.67%.The difference between the two groups was statistically significant (P 〈 0.05) .After treatment,the blood uric acid,the disappearance time of joint pain,and scores of main clinical symptoms (joint pain,swelling and limitation of activity ) of the two groups were significantly lowered than before treatment ( P 〈 0.01 ) ,and the treatment group was better than the control group ( P 〈 0.05 or P 〈 0.01 ) .Conelusion:Needlescope combined with conventional medicine is effective in the treatment of acute stage of intractable gout.
出处
《风湿病与关节炎》
2017年第5期28-30,44,共4页
Rheumatism and Arthritis
关键词
难治性痛风
急性期
微创针刀镜
疗效观察
intractable gout
acutestage
needlescope
observation on the clinicalefficacy