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Comparison of blood rheological models in patient specific cardiovascular system simulations

Comparison of blood rheological models in patient specific cardiovascular system simulations
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摘要 Newtonian, Quemada and Casson blood viscosity models are implemented in order to simulate the rheological behavior of blood under pulsating flow conditions in a patient specific iliac bifurcation. The influence of the applied blood constitutive equations is monitored via the wall shear stress (WSS) distribution, magnitude and oscillations, non-Newtonian importance factors, and viscosity values according to the shear rate. The distribution of WSS on the vascular wall follows a pattern which is independent of the theological model chosen. On the other hand, the WSS magnitude and oscillations are directly related to the blood constitutive equations applied and the shear rate. It is concluded that the Newtonian approximation is satisfactory only in high shear and flow rates. Moreover, the Newtonian model seems to overestimate the possibility for the formation of atherosclerotic lesions or aneurysms at sites of the vascular wall where the WSS are oscillating. Newtonian, Quemada and Casson blood viscosity models are implemented in order to simulate the rheological behavior of blood under pulsating flow conditions in a patient specific iliac bifurcation. The influence of the applied blood constitutive equations is monitored via the wall shear stress (WSS) distribution, magnitude and oscillations, non-Newtonian importance factors, and viscosity values according to the shear rate. The distribution of WSS on the vascular wall follows a pattern which is independent of the theological model chosen. On the other hand, the WSS magnitude and oscillations are directly related to the blood constitutive equations applied and the shear rate. It is concluded that the Newtonian approximation is satisfactory only in high shear and flow rates. Moreover, the Newtonian model seems to overestimate the possibility for the formation of atherosclerotic lesions or aneurysms at sites of the vascular wall where the WSS are oscillating.
出处 《Journal of Hydrodynamics》 SCIE EI CSCD 2017年第2期293-304,共12页 水动力学研究与进展B辑(英文版)
基金 supported by the National Strategic Reference Framework(NSRF)2007-2013 project DEKA:“Integrated prognostic system for risk assessment in stent implantations for Abdominal Aortic Aneurysm repair”(Grant No.09SYN-12-1153)
关键词 Key words: Blood flow simulation patient specific geometries geometry reconstruction non-Newtonian models wall shear stress pulsating flow Key words: Blood flow simulation, patient specific geometries, geometry reconstruction, non-Newtonian models, wall shear stress,pulsating flow
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