硝酸甘油软膏在腋臭微创切除术后中的临床应用

Application of Nitroglycerin Ointment in healing of wound after bromidrosis minimal invasive

目的观察硝酸甘油软膏对腋臭微创术后创面愈合中的作用。方法随机抽取就诊于新疆医科大学第一附属医院整形外科门诊的腋臭患者40例(2016年9月—2017年03月),对40例腋臭患者进行随机分组,分为观察组和对照组,每组各20例,对观察组患者于术后即刻以及每次换药后于术区创面涂以硝酸甘油软膏,对于对照组则单独使用小油纱覆盖。于每次换药时观察观察组与对照组患者术区皮瓣发生溃疡或坏死等术后并发症的发生情况,对观察组与对照组术区创面愈合的时间进行观察并做记录,并于换药后对观察组与对照组的疼痛程度用微笑疼痛评分表进行评估。结果 (1)观察组术区皮瓣愈合良好,未出现创面发黑坏死等情况,对照组术区皮瓣出现缺血、发黑等情况的有3例患者;观察组与对照组并发症进行比较后差异有统计学意义(P<0.05)。(2)观察组术区创面及切口的的平均愈合时间为[(7.12±1.38)d]显著低于对照组[(10.71±1.34)d],两组比较差异有统计学意义(P<0.05)。(3)观察组患者术区疼痛程度低于对照组术区疼痛程度。结论在腋臭微创切除术后,使用硝酸甘油软膏不仅可有效缩短患者切口愈合时间并可降低术区皮瓣发生溃疡或坏死等并发症情况的发生,同时可降低术后术区疼痛程度。

Objective To observe the clinical effect of nitroglycerin ointment on the wound repair after surgery of bromidrosis resection. Methods From September 2016 to March 2017,40 cases of patients that received surgery of bromidrosis resection were selected. All patients were randomly divided into treatment group and control group with 20 cases in each group. In treatment group, Nitroglycerin Ointment were applied on the surface of flap. While the control group was treated with oil gauze on the surface of flap. The postoperative complications including flap ulcer or necrosis, wound healing time and degree of postoperative pain in two groups were observed, respectively. Results ① No flap ulcer or necrosis was found in the treatment group. While these were found in 3 cases of the control group, which was significant higher than in treatment group （P 〈 0.05） , ② The average wound healing time in treatment group [（7.12±1.38） d] was significantly faster than that in control group [ （10.71±1.34d） d] （P 〈 0.05） . ③ Patients in the treatment group were significantly lower in pain. Conclusion Application of Nitroglycerin Ointment can significantly accelerate wound healing, reduce the incidence of skin flap necrosis and relieve the pain of incision after armpits resection.