中国生物样本库:路在何方?

China biobank: Where are we going?

标准化的生物样本既是基因组、功能基因组等基础、临床研究的源头,又是实现分子诊断标志物及药物靶点的大样本验证、快速实现转化与个性化精准诊疗的核心环节。生物样本库已成为大科学基础工程,备受医学界、生命科学界、生物医药工业界、产业界、资本界乃至政界等的高度关注,并得到快速发展。然而,中国生物样本库的发展任重道远,随着中国医药生物技术协会组织生物样本库分会、全国生物样本标准化技术委员会及中国生物样本库联盟等里程碑式组织相继成立,在标准化、特色化、学科化、集约化、资源化、价值化等方面做了大量卓有成效的开创性工作,为实现生物样本资源在生物医药产业链各环节的充分应用,开启了中国生物样本库标准化建设的新时代。

Standardized bio-specimen is the basic source for genome, functional genomics and clinical research, as well as the key for verification of molecular markers for diagnosis of large sample and drug target validation, rapid transformation and personalized precision diagnosis. Biobank has become to be scientific foundation and high degree of concern about biobank are paid by medical community, life science, bio-pharrnaceutical industry, industry circles, capital circles and government. In this situation, rapid development of Biobank has been achieved. However, the China Biobank development is a tremendous task. By the establishment of the China Medical Biotechnology Association Biobank Branch, the National Technical Committee 559 on Bio-specimen of Standardization Administration of China and China Biobank Alliance, a lot of pioneering work on the standardization, specialization, disciplinization, intensity, resource utilization and valuation of biobank has been done to achieve the full application of bio-specimen in bio-pharmaceutical industry and the new era of standardization of China Biobank construction.