摘要
随着肠-肝轴机制研究的不断深入,肠道菌群与多种慢性肝脏疾病如非酒精性脂肪性肝病、酒精性肝病、肝硬化等相关性研究日益增多。肠道菌群通过肠道菌群失调、物质能量代谢改变及免疫反应激活等机制在多种肝脏疾病发生发展中发挥重要作用。本文对肠道菌群与慢性肝脏疾病关系的研究进展进行综述。
With the further study of gut-liver axis, more and more studies focus on the relationships between gut microbiota and various chronic liver diseases including non-alcoholic fatty liver disease, alcoholic liver disease, and liver cirrhosis. Gut microbiota may play an important role in the development of various chronic liver diseases through gut dysbiosis, change of material and energy metabolism, and activation of immune responses, etc. This article reviews the role of gut microbiota in chronic liver diseases.
出处
《中国微生态学杂志》
CAS
CSCD
2017年第5期610-614,共5页
Chinese Journal of Microecology
基金
国家自然科学基金资助项目(81370546)
关键词
肠道菌群
肠-肝轴
非酒精性脂肪性肝病
酒精性肝病
肝硬化
Gut microbiota
Non-alcoholic fatty liver disease
Gut-liver axis
Alcoholic liver disease
Liver cirrhosis
