肺络与特发性肺纤维化病机探讨

Discussion on Correlation between Pulmonary Collateral and Pathogenesis of Idiopathic Pulmonary Fibrosis

对肺络的进化史进行考证,认为肺出现在高等脊椎动物时期,主要由内胚层和外胚层分化而来,经络由中胚层分化而来;通过对肺络的文献学考证,认为肺络具有贯通营卫、溢奇邪、渗灌气血等功能。根据肺络的功能特点和肺心相关理论,提出肺纤维化病机为心火灼肺、阴虚络瘀,为提高特发性肺纤维化的临床疗效提供新的理论基础。

Through the research of the evolutionary history of pulmonary collateral,it is found that the lung appeared in the higher vertebrate animal period and its evolution had something to do with the ectoderm and the endoderm,the collaterals evolved from the mesoderm. Through the research of the documents about pulmonary collateral,it is found that the pulmonary collateral had the function of linking nutritive qi with defensive qi,elevating pathogenic qi,irrigating qi and blood,etc. Based on the functional characteristics of the pulmonary collateral and the theory of correlation between the lung and the heart,the pulmonary fibrosis pathogenesis is proposed as the burning of the lung by the heart fire which causes yin deficiency and blood stasis in pulmonary collateral. It provides a new theoretical basis for improving the clinical efficacy of idiopathic pulmonary＂ fibrosis.