老年阴道炎症患者阴道分泌物假丝酵母菌和阴道毛滴虫感染状况分析

Prevalence of Candida and Trichomonas vaginalis infection in vaginal secretions of patients with senile vaginitis

目的分析老年性阴道炎患者阴道分泌物中假丝酵母菌和阴道毛滴虫感染状况,以期为阴道分泌物假丝酵母菌和阴道毛滴虫感染的防治提供更多循证医学证据。方法收集医院2013年6月-2016年6月收治的老年性阴道炎患者546例,使用显微镜检测假丝酵母菌和阴道毛滴虫感染情况。结果 546例老年性阴道炎患者中检出假丝酵母菌感染114例(20.9%),阴道毛滴虫感染132例(24.2%);假丝酵母菌感染≤70岁检出率31.4%,71~80岁检出率12.7%,≥81岁检出率5.4%,组间比较差异有统计学意义(P<0.05);毛滴虫感染在≤70岁检出率37.5%,71~80岁检出率14.4%,≥81岁检出率1.8%,组间比较差异有统计学意义(P<0.05);农民、个体商户、单位职工中老年性阴道炎患者假丝酵母菌感染率分别为32.8%、16.9%和9.4%,组间比较差异有统计学意义(P<0.05),其中农民显著高于个体商户人群(P<0.05),个体商户又显著高于单位职工人群(P<0.05);农民、个体商户、单位职工中老年性阴道炎患者毛滴虫感染率分别为19.4%、31.9%和16.0%,农民与单位职工人群二者均显著低于个体商户人群(P<0.05);春季、夏季、秋季和冬季老年性阴道炎患者假丝酵母菌感染率分别为36.0%、17.4%、13.9%和12.5%,春季显著高于夏季、秋季和冬季(P<0.05)。结论老年性阴道炎患者阴道分泌物中假丝酵母菌和阴道毛滴虫检出率高,做好相关的防护有利于假丝酵母菌和阴道毛滴虫的防治。

OBJECTIVE To investigate the prevalence of Candida and Trichomonas vaginalis infection in vaginal secretions of patients with senile vaginitis so as to provide more evidence-based medical evidence for prevention and treatment of the Candida and T.vaginalis infection in vaginal secretions.METHODS A total of 546 patients with senile vaginitis who were treated in the hospital from Jun 2013 to Jun 2016 were enrolled in the study,and the provenance rate of Candida and T.vaginalis infection was detected by using microscope.RESULTS Of the 546 patients with senile vaginitis,114 （20.9%） had Candida infection,and 132 （24.2%） had T.vaginalis infection.The prevalence rate of Candida infection was 31.4% in the patients aged no more than 70 years old,12.7% in the patients aged between 71 and 80 years old,5.4% in the patients aged no less than 81 years old,and there was significant between-group difference （P〈0.05）.The prevalence rate of T.vaginalis infection was 37.5% in the patients aged no more than 70 years old,14.4% in the patients aged between 71 and 80 years old,1.8% in the patients aged no less than 81 years old,and there was significant between-group difference （P〈0.05）.Among the patients with senile vaginitis,the incidence rate of Candida infection was 32.8% in peasants,16.9% in self-employed businessmen,9.4% in enterprise employees,and there was significant between-group difference （P〈0.05）;the incidence rate of Candida infection was significantly higher in peasants than in self-employed businessmen （P〈0.05）,and the incidence rate of Candida infection was significantly higher in self-employed businessmen than in enterprise employees （P〈0.05）.Among the patients with senile vaginitis,the incidence rate of T.vaginalis infection was 19.4% in peasants,31.9% in self-employed businessmen,16.0% in enterprise employees;the incidence rate of T.vaginalis infection was significantly lower in peasants and enterprise employees than in selfemployed businessmen （P〈0.05）.The incidence rate of Candida infection was 36.0% in spring,17.4% in summer,13.9% in autumn,12.5% in winter;the incidence rate of Candida infection was significantly higher in spring than in summer,autumn,and winter （P〈0.05）.CONCLUSION The prevalence rates of Ca ndida and T.vaginalis are high in vaginal secretions of the patients with senile vaginitis.It is necessary to take targeted prevention measures so as to prevent and treat the Candida and T.vaginalis infection.