两步灌肠法对中医药保留灌肠治疗溃疡性结肠炎效果影响的Meta分析

目的评价两步灌肠法即先行清洁灌肠而后行保留灌肠与常规保留灌肠法相比对中医药治疗溃疡性结肠炎患者的效果。方法采用中外文电子数据库系统评价溃疡性结肠炎患者两步保留灌肠的临床随机对照试验（RCT）。结果共纳入RCT文献10篇，病例数共763例。结果显示两步灌肠法与常规保留灌肠法相比能有所提高中医药灌肠的治疗效果（P〈0．05）。结论应用两步灌肠法的改良护理措施在提高中医药治疗溃疡性结肠炎效果方面显示其优势，但RCT文献质量普遍不高，仍有待临床开展多中心、大样本、高质量的临床随机对照试验来证实。

Objective To systematically evaluate the effectiveness of two-step retention enema of Chinese medicine in patients with ulcerative colitis. Methods Clinical randomized controlled Trials （ RCTs ） that assessed the effectiveness of two-step retention enema in patients with ulcerative colitis were systematically reviewed using Chinese and foreign language electronic databases. Results Ten RCTs were included. The results supported the effectiveness of two-step retention enema on improving effect of herbal therapy compared with regular retention enema （ P〈0.05 ） . Conclusion The nursing intervention of two-step retention enema is effective in improving the effectiveness of herbal therapy. Actually, the quality of related RCTs literatures are not very high, multi-centered and large-scale randomized controlled trials are needed to confirm its effectiveness.