摘要
A novel coumarin-based "turn-on" fluorescent probe SS-1 was developed for selective detection of SO_2 derivatives in 100% water solution among reactive sulfur species(RSS). The detection limit of the method was 91.7 nM. Moreover, the probe exhibited low cytotoxicity and was successfully applied in the imaging of endogenously generated SO_2 in HeLa cells.
A novel coumarin-based ＂turn-on＂ fluorescent probe SS-1 was developed for selective detection of SO2 derivatives in 100% water solution among reactive sulfur species（RSS）. The detection limit of the method was 91.7 nM. Moreover, the probe exhibited low cytotoxicity and was successfully applied in the imaging of endogenously generated SO2 in HeLa cells.
基金
supported by the National Program on Key Basic Research Project of China (2012CB720603)
the National Natural Science Foundation of China (21232005, 21572147, J1103315)
