临床药师干预对急性脑梗死介入术后患者用药依从性及疗效的影响

Effect of clinical pharmacist intervention on drug compliance and efficacy of patients after acute cerebral infarction

目的探讨临床药师干预对急性脑梗死介入术后患者用药疗效及依从性的影响。方法将73例急性脑梗死并进行介入术治疗的患者随机分为对照组36例和试验组37例。出院时,对照组采用常规的护士发药和简单宣讲方式;试验组由临床药师进行用药干预指导。半年后,随诊并评价2组患者的用药效果及依从性。结果试验组和对照组的总有效率分别为70.27%(26/37例)和47.22%(17/36例);掌握用药方法的总体合格率分别为78.38%(29/37例)和52.78%(19/36例);用药依从性较好率分别为56.76%(21/37例)和30.56%(11/36例);自动停药率分别为0(0/37例)和19.44%(7/36例),差异均有统计学意义(均P<0.05)。结论临床药师干预可明显提高急性脑梗死介入术后患者的治疗效果,提高患者对用药方法的掌握程度和用药依从性。

Objective To analyze effect of clinical pharmacist intervention on drug compliance and efficacy of patients after acute cerebral in- farction. Methods A total of 73 patients with acute cerebral infarction and intervention were randomly divided into control group （36 cases） and treatment group （37 cases）. At the time of discharge, the control group adopted conventional nurse dispensing and short - answer presentation mode. The treatment group was instructed by the clinical pharma- cist. Six months later, follow - up and evaluation of the two groups of patients with drug effects and compliance. Results The total effective rate was 70. 27% （26/37 cases） and 47.22% （17/36 cases） in the treat- ment group and the control group, respectively. The overall pass rate of the mastery of medication was 78.38% （29/37 cases） and 52.78% （ 19/36 cases）. The rate of drug withdrawal was 56. 76% （ 21/37 cases） and 30. 56% （ 11/36 cases） respectively. The rates of automatic withdrawal were 0 （0/37 cases） and 19. 44% （7/36 cases） There was statistical significance （P 〈 0. 05 ）. Conclusion Clinical pharmacist in- tervention can significantly improve the therapeutic effect of patients with acute cerebral infarction after intervention, which improve the degree of medication and medication compliance.