异丙酚复合瑞芬太尼在肺叶切除术单肺通气麻醉中的应用效果评价

Evaluation of the Effect of Propofol Combined with Remifentanil in Single Lung Ventilation Anesthesia with Lobectomy

目的:评价异丙酚复合瑞芬太尼在肺叶切除术单肺通气麻醉中的应用效果。方法:选取2014年5月~2016年某院收治的肺叶切除术单肺通气患者86例作为研究对象,按照不同麻醉方法分为对照组和试验组,各组均为43例患者,对照组采用异丙酚复合芬太尼麻醉,试验组采用异丙酚复合瑞芬太尼麻醉,观察并比较两组麻醉效果。结果:试验组麻醉后各时间段的肺内分流量均显著低于对照组,组间出现的差异具有统计学意义(P<0.05);两组开眼时间、恢复自主呼吸时间、拔管时间进行统计比较,试验组均短于对照组,组间差异显著(P<0.05)。结论:在肺叶切除术单肺通气麻醉中应用异丙酚复合瑞芬太尼有利于维持血流动力学稳定,缩短术后清醒时间,安全性高,具有积极的临床选择和推广价值。

Objective： To evaluate the effect of propofol combined with remifentanil in single lung ventila-tion anesthesia with lobectomy. Methods： A total of 86 patients with pulmonary ventilation were selected from May 2014 to 2016. The patients were divided into control group and experimental group according to different anesthesia methods with 43 patients in each group. The control group were treated with Propofol combined with fentanyl anesthesia and the experimental group using propofol combined remifentanil anesthesia. Then observe and compare the anesthesia effect of the two groups. Results： Compared with the control group, the difference between the two groups was statistically significant （P〈0.05）. In the two groups, the time of spontaneous breathing and the time of extubation were compared with the control group, the difference between the two groups was significant （P〈0.05）. Conclusion： Propofol combined with remifentanil is effective in maintaining hemodynamic stability, shortening postoperative awake time, high safety, and has positive clinical choice and popularization value in lobectomy with single lung anesthesia.