阿托品联合奥美拉唑治疗急性胃炎患者的临床观察

Clinical Observation of the Treatment of Acute Gastritis Patients by Atropine Combined with Omeprazole

目的:探讨阿托品联合奥美拉唑治疗急性胃炎患者的临床效果。方法:选取2015年3月-2016年3月笔者所在医院收治的100例急性胃炎患者进行分析研究,根据随机对照原则均分为两组,其中50例应用阿托品联合奥美拉唑治疗的患者为观察组,50例单独应用奥美拉唑治疗的患者为对照组,分析比较两组患者的临床治疗效果。结果:观察组患者临床治愈率90.0%,治疗有效率98.0%,明显高于对照组的72.0%、92.0%,两组比较差异有统计学意义(P<0.05)。观察组患者治疗期间心悸、恶心、腹泻及口干发生率分别为2.0%、4.0%、2.0%、4.0%,明显低于对照组的8.0%、10.0%、10.0%、12.0%,两组比较差异有统计学意义(P<0.05)。结论:阿托品联合奥美拉唑治疗急性胃炎具有较好的临床效果,可以有效降低不良反应发生率,具有较好的临床应用效果及应用价值,值得进一步推广应用。

Objective： To discuss the clinical effect of treating acute gastritis patients by Atropine combined with Omeprazole（OME）.Method： 100 cases of acute gastritis patients received and cured by our hospital from March 2015 to March 2016 were selected for analytical investigation and evenly divided into two groups according to the randomized control principle.50 cases of them who were given Atropine combined with OME for therapy were as the observation group and the other 50 cases with sole application of OME were as the control group.The clinieal treatment effect of the two groups of patients were analyzed and compared. Result： The clinical cure rate of patients in the observation group was 90.0% and the therapy effective rate was 98.0%, which were much higher than 72.0% and 92.0% of the control group.The comparative difference of the two groups was statistical significance（P〈0.05）.During the treatment period, the clinical morbidities of palpitation, nausea, diarrhea and xerostomia for patients in the observation group were 2.0%, 4.0%, 2.0% and 4.0%, obviously lower than 8.0%, 10.0%, 10.0%, 12.0% of the control group.The comparative difference of the two groups was statistical significance（P〈0.05）.Conclusion： The treatment by joint use of Atropine and OME has preferable clinical effect.The treatment method can effectively reduce the occurrence rate of untoward effect with preferable clinical application effect and application value, and it is deserved further popularization and application.