穴位埋线联合麻杏石甘茶治疗小儿咳嗽变异性哮喘临床研究

Clinic Study of Acupoint Catgut Embedding and Maxing Shigan Tea in Treating Infant CVA

目的:研究穴位埋线联合麻杏石甘茶对小儿咳嗽变异性哮喘临床疗效和安全性分析,以寻找多途径治疗小儿咳嗽变异性哮喘的新方法。方法:选取2013年3月—2015年3月郑州市中医院、郑州市儿童医院、河南中医学院第三附属医院儿科门诊收治的240例小儿咳嗽变异性哮喘,将患者随机分成两组,对照组予以孟鲁司特钠咀嚼片和麻杏石甘茶治疗,治疗组予以穴位埋线+麻杏石甘茶治疗。治疗后观察两组患者的临床疗效、免疫功能情况及不良反应情况。结果:两组患者治疗总疗效比较无差异(P>0.05);两组患者咳嗽缓解时间、咳嗽消失时间及治疗前、后咳嗽症积分比较均无差异(P>0.05);随访9个月后,治疗组患者咳嗽复发次数少于对照组(P<0.05);治疗前及治疗后两组患者lg G、lg E、lg A、PAF比较无差异(P>0.05),疗后9个月治疗组lg G、lg E、lg A、PAF水平优于对照组(P<0.05),两组患者治疗前、后及疗后9个月CD4/CD8比较均无差异(P>0.05),所有指标与同组治疗前比较均有差异(P<0.05);两组患者治疗前及治疗后Fe NO值比较均无差异(P>0.05),疗后9个月比较治疗组值低于对照组(P<0.05);患者不良反应情况无统计学意义。结论:穴位埋线联合口服麻杏石甘茶治疗小儿CVA临床疗效确切,可调节机体免疫状态,提高患儿抵抗力,服药时间短,操作相对简便,痛苦较小,安全性高,具有良好的推广前景。

Objective：To investigate the clinic effect and safety of acupoint catgut embedding and Maxing Shigan Tea in treating infant CVA to find more new methods. Methods：A total of 240 cases with CVA in Zhengzhou Hospital of TCM, Children＇s Hospital of Zhengzhon, The Third Affiliated Hospital of Henan College of Traditional Chinese Medicine from March 2013 to March 2015 were selected and divided into two groups. The control group was given Montelukast chewable tablet and Maxing Shigan Tea and the treatment group was given acupoint catgut embedding and Maxing Shigan Tea. Observe the clinic effect, immunologic function and adverse reactions of two groups. Results ：The clinic effect of the two groups had no difference （P 〉 0. 05 ）. The cough remission time, cough disappearing time and cough syndrome integral before and after treatment had no difference （ P 〉 0. 05 ）. After 9 months, cough recurrent times of observation group was less than that of the control group （P 〈 0. 05 ）. lgG, lgE, lgA and PAF before and after treatment of two groups had no difference （ P 〉 0. 05 ）. After 9 months, lgG, lgE, lgA and PAF of observation group were better than those of the control group （ P 〈 0. 05 ）. CD3/CDs of two groups before and 9 months after treatment had no difference [ P 〉 0. 05 ）. All indexes compared with those before treatment had significant difference （ P 〈 0. 05 ）. FeNO of two groups before and after treatment had no difference （ P 〉 0. 05 ）. After 9 months, treatment group＇ s was lower than the control group＇ s （ P 〈 0. 05 ）. The adverse reactions of patients had no statistic significance. Conclusion ： Acupoint catgut embedding and Maxing Shigan Tea in treating infant CVA has significant effect. It can regulate body＇s immune status and improve infant resistance. The time of taking medicine is short and the medicine can be easily taking with less pain and high safety and is worthy of wide application.