高压氧治疗进展性脑梗死的疗效及对血浆C-反应蛋白含量的影响

Effect of hyperbaric oxygen therapy on progressive cerebral infarction and its effect on plasma C-reactive protein

目的:探讨高压氧治疗进展性脑梗死的疗效及对血浆C-反应蛋白含量的影响。方法:选取2013年10月至2016年10月收治的进展性脑梗死患者180例作为研究对象,按照随机数字表法分为观察组和对照组,各90例。对照组给予尿激酶溶栓治疗,观察组在对照组治疗的基础上给予高压氧治疗,比较两组患者的治疗效果及两组患者治疗前、后血浆C-反应蛋白(C-reactive protein,CRP)含量的变化。结果:治疗前两组患者的美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分与CRP含量比较差异无统计学意义(P>0.05),治疗后观察组患者的NIHSS评分与CRP含量均优于对照组(P<0.05)。结论:高压氧治疗进展性脑梗死的疗效肯定,可提高患者的治愈率,改善患者的预后,降低致残率,降低患者感染的风险,值得推广使用。

Objective： To investigate the effect of hyperbaric oxygen therapy on progressive cerebral infarction and its effect on plasma C-reactive protein. Methods： 180 patients with progressive cerebral infarction from October 2013 to October 2016 were collected and randomly divided into observation group and control group according to random number table,90 cases in each group. The control group was treated with urokinase thrombolytic. The observation group was given hyperbaric oxygen on the basis of the therapy in the control group. The therapeutic effect of the two groups and the changes of plasma C-reactive protein（ CRP） before and after treatment between the two groups were compared. Results： There was no significant difference in National Institute of Health stroke scale（ NIHSS） score and CRP before treatment between the two groups（ P〉0.05）. NIHSS score and CRP after treatment in the observation group were superior to those of the control group,the difference statistically significant（ P〈0. 05）. Conclusion： The effect of hyperbaric oxygen therapy on progressive cerebral infarction was affirmed,which can enhance the cure rate in patients,improve the prognosis and reduce the disability rate. It also can reduce the risk of infection. This treatment can be used.