四川省居民2004—2013年恶性肿瘤死因及减寿分析

Mortality and YPLL of malignant tumor in Sichuan province,2004-2013

目的了解四川省2004—2013年恶性肿瘤死亡情况及其所造成的潜在寿命损失,为慢性病防控工作提供参考依据。方法收集四川省2004年1月—2013年12月全人群死因监测点死亡登记报告资料,应用死亡登记信息系统统计与分析工具、Joinpoint 4.2.0.2软件、SPSS 18.0软件分析恶性肿瘤粗死亡率、标化死亡率及其变化趋势和潜在寿命损失年数。结果四川省居民恶性肿瘤死亡率从2004年的129.66/10万上升至2013年的191.09/10万,呈上升趋势(APC=4.57%,t=11.84,P<0.01),标化死亡率从2004年的122.58/10万上升至2013年的130.48/10万,上升趋势无统计学意义(P>0.05);男性恶性肿瘤死亡率高于女性,死亡率性别比为1.95~2.17:1,标化死亡率性别比为1.85~2.05∶1;2004—2013年居于四川省前10位的恶性肿瘤依次为肺癌、肝癌、食管癌、胃癌、结直肠癌、白血病、乳腺癌、鼻咽癌、膀胱癌、宫颈癌,除胃癌外的其他9种恶心肿瘤死亡率均呈上升趋势(均P<0.05);四川省2004、2009、2013年恶性肿瘤所致居民潜在寿命损失年数(YPLL)分别为157 532.0、204 171.0、196 413.0人年,潜在寿命损失率(YPLLR)分别为14.04%、16.93%、15.83%。结论四川省恶性肿瘤死亡率总体呈上升趋势,肺癌、肝癌、食管癌是造成该地区潜在寿命损失的主要恶性肿瘤。

Objective To analyze the mortality of malignant tumor and years of potential life lost （YPLL） caused by malignant tumor in Sichuan province during 2004 and 2013 for the prevention and control of chronic diseases. Methods Death registry data for residents in 20 disease surveillance sentinel sites （ 12 districts and 8 counties） in Sichuan province during 2004 -2013 were collected and the mortality of malignant tumor was analyzed. Crude mortality rate, standardized mortality rate, trend of mortality rate and YPLL were calculated and analyzed with DeathReg, Joinpoint 4. 2. 0. 2 and SPSS 18.0. Results The mortality rate of malignant tumor in Sichuan province showed an upward trend, increasing from 129.66/100 000 in 2004 to 191.09/100 000 in 2013 （P 〈0. 01 ） ;the mortality rates of malignant tumor were higher in the male residents than in the females,with the male to female ratios of 1.95 -2. 17：1 and the standardized mortality ratios of 1. 85 - 2. 05 ： 1. From 2004 to 2013 ,the top 10 malignant tumors with higher mortalities in Sichuan province were lung cancer,liver cancer,esophageal cancer,gastric cancer,colorectal cancer,leukemia,breast cancer,nasopharyngeal carcinoma,bladder cancer, and cervical cancer and the mortality of all the cancers showed an upward trend （P 〈 0. 01 ） except for gastric cancer. The YPLL caused by malignant tumor in 2004,2009,2013 were 157 532 years,204 171 years,and 196 413 years, while the YPLL rate were 14. 04%, 16. 93% ,and 15. 83% ,respectively. Conclusion Mortality of malignant tumor in Sichuan province showed an upward trend generally and lung, liver, and esophageal cancer were main contributors to YPLL due to malignant tumor.