摘要
Vogt-小柳原田综合征(Vogt-Koyanagi-Harada syndrome,VKH综合征)是一种由自身免疫反应引起的攻击黑色素细胞抗原的致盲眼病,往往还会侵袭耳、脑(脊)膜、毛发以及皮肤等器官。早期正确诊断与及时治疗对视力预后尤为重要。目前糖皮质激素为一线药物。此外,难治性葡萄膜炎可选择免疫抑制剂和生物制剂等药物治疗。
Vogt- Koyanagi- Harada (VKH) syndrome is an autoimmune disease attacking against pigmented cells, resulting in blindness and usually affecting multiple organs including ears, meninges, hair and skin. Correct diagnosis and immediate treatment in the early stage is vital to visual prognosis. Currently, corticosteroids is first- line drug. In addition, VKH patients refractory to corticosteroids can choose other treatment such as immunosuppressive agents and biological agents.
出处
《国际眼科杂志》
CAS
2017年第6期1082-1086,共5页
International Eye Science