衰弱表型与老老年患者血压的关系研究

Relationship between Frailty Phenotype and Blood Pressure in the Very Elderly Patients

目的分析衰弱表型与老老年患者血压的关系。方法选取2014—2015年在宜昌市中心人民医院老年科门诊及住院就诊的老老年患者80例,根据衰弱表型分为正常者30例(正常组)、衰弱前期者27例(衰弱前期组)和衰弱者23例(衰弱组)。比较3组患者临床资料、血压及血压变异性指标。结果 3组患者性别、年龄、体质指数、糖化血红蛋白、总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇及肌酐清除率比较,差异均无统计学意义(P>0.05)。3组患者24 h平均舒张压和24 h舒张压变异性比较,差异无统计学意义(P>0.05);衰弱前期组患者24 h平均收缩压低于正常组和衰弱组,24 h收缩压变异性高于正常组和衰弱组(P<0.05)。结论衰弱表型与老老年患者收缩压及收缩压变异性有关。

Objective To analyze the relationship between frailty phenotype and blood pressure in the very elderly patients. Methods From 2014 to 2015, a total of 80 very elderly outpatients and inpatients were selected in the Central People＇s Hospital of Yichang, and they were divided into A group （ without frailty, n = 30）, B group （ with pre - frailty, n = 27） and C group （with frailty, n = 23 ） according to frailty phenotype. Clinical data, blood pressure and blood pressure variability indicators were compared among the three groups. Results No statistically significant differences of gender, age, BMI, HbA^o, TC, HDL-C, LDL-C or Ccr was found among the three groups, nor was 24 -hour mean diastolic blood pressure or 24 - hour diastolic blood pressure variability among the three groups （ P 〉 0. 05 ） ; 24 - hour mean systolic blood pressure of B group was statistically significantly lower than that of A group and B group, respectively, while 24 - hour mean systolic blood pressure variability was statistically significandy higher than that of A group and C group, respectively （ P 〈 0. 05 ）. Conclusion Frailty phenotype is closely correlated with systolic blood pressure and systolic blood pressure variability in the very elderly patients.