5Chen J W,Chen Y H,Lin S J. Long-term exposure to oxidized low density lipoprotein enhances tumor necrosis factor-alpha stimulated endothelial adhesiveness of monocytes by activating superoxide generation and redox-sensitive pathways[J]. Free Radic Biol Med,2006,40:817-826.
6Hoyle G W. Mitigation of chlorine lung injury by increasing cyclic AMP levels[J]. Proc Am Thorac Soc,2010,7(4):284-289.
7Lugnier C.Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents[J].Pharmacology & Therapeutics,2006,109(3):366-398.
8Rabe K F. Update on roflumilast,a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary disease[J].Br J Pharmacol,2011,163(1):53-67.
10Taegtmeyer A B,Leuppi J D,Kullak-ublick G A. Roflumilast——A phosphodiesterase-4 inhibitor licensed for add-on therapy in severe COPD[J].Swiss Med Wkly,2012,25(2):142.
