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替吉奥联合顺铂与多西他赛联合顺铂治疗晚期食管癌的临床效果比较 被引量:3

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摘要 目的观察比较替吉奥联合顺铂与多西他赛联合顺铂治疗晚期食管癌的临床效果。方法将92例医院收治的晚期食管癌患者随机分为对照组和观察组,每组46例。对照组采用替吉奥联合顺铂治疗,观察组采用多西他赛联合顺铂治疗,将2组患者的近期疗效、生存率与不良反应发生率进行比较。结果观察组总有效率为78.26%,对照组总有效率为71.74%;观察组不良反应总发生率为34.78%,对照组不良反应总发生率为41.30%;观察组生存率为65.22%,对照组生存率为60.87%,差异均无统计学意义(P>0.05)。结论替吉奥联合顺铂与多西他赛联合顺铂在治疗晚期食管癌方面均有较明显的效果,2种治疗方案在近期治疗效果、生存率及不良反应发生率上不存在显著差异,均能够对晚期食管癌患者进行有效治疗,具有临床推广应用价值。
出处 《临床合理用药杂志》 2017年第14期59-60,共2页 Chinese Journal of Clinical Rational Drug Use
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