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恩替卡韦治疗慢性乙肝的效果研究

Study on Entecavir Effect in the Treatment of Chronic Hepatitis B
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摘要 目的对恩替卡韦应用于慢性乙肝临床治疗中的效果进行研究。方法选取2014年2月—2016年10月在我院接受治疗的128例慢性乙肝患者作为研究对象,并1:1随机分为参照组(给予常规综合治疗)和实验组(给予恩替卡韦治疗),每组各64例,对两种不同治疗方式的效果进行对照研究。结果实验组患者治疗总有效率为92.19%,高于参照组(73.44%);实验组患者HBV-DNA阴转率为79.69%,高于参照组(53.13%),组间对比,差异具有统计学意义(P<0.05)。结论恩替卡韦应用于慢性乙肝临床治疗中的效果显著。 Objective To study the effect of entecavir in the treatment of chronic hepatitis B. Methods 128 cases of patients with chronic hepatitis B treated in our hospital from February 2014 to October 2016 were selected as the subjects, and 1:1 were randomly divided into reference group (given conventional treatment) and experimental group (given entecavir treatment), 64 cases in each group. The effects of two different treatments were compared. Results The total effective rate in the experimental group was 92.19%, which was higher than the reference group (73.44%). The HBV-DNA negative conversion rate was 79.69% in the experimental group, which was higher than the reference group (53.13%), between groups, the difference was statistically significant (P 〈 0.05). Conclusion Entecavir is effective in the treatment of chronic hepatitis B.
作者 樊微微
出处 《中国卫生标准管理》 2017年第10期72-73,共2页 China Health Standard Management
关键词 恩替卡韦 慢性乙肝 效果 entecavir chronic hepatitis B effect
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