果糖二磷酸钠治疗小儿病毒性心肌炎疗效评估

Fructose Diphosphate in the Treatment of Viral Myocarditis in Children

目的分析果糖二磷酸钠治疗小儿病毒性心肌炎的临床效果。方法选取2015年1月30日—2017年1月31日来我院就医的小儿病毒性心肌炎患者150例作为本次研究对象,通过动态化随机单双号分组的方法,将其分为两组,分别给予果糖二磷酸钠、黄芪治疗,探究两组患者治疗有效率、CK、LDH、CKMB、临床症状消失时间、体征消失时间的差异性。结果观察组患者的治疗有效例数为70例,CK:(121.55±30.41)IU/L、LDH:(150.24±30.24)U/L、CKMB:(164.24±15.24)IU/L、临床症状消失时间:(16.24±1.54)天、体征消失时间:(15.21±1.11)天,对照组患者:治疗有效例数为55例、CK:(169.65±30.66)IU/L、LDH:(188.66±34.56)U/L、CKMB:(195.69±16.87)IU/L、临床症状消失时间:(25.36±2.54)天、体征消失时间:(26.66±3.33)天,两组患者各指标对比,差异均具有统计学意义(P<0.05)。结论果糖二磷酸钠治疗小儿病毒性心肌炎具有一定的应用效果。

Objective Tn analyze the clinical effect of fructose diphosphate in the treatment of viral myocarditis in children. Methods 150 cases of patients with viral myocarditis from January 30, 2015 to January 31, 2017 were selected as the study subjects, and the subjects were divided into two groups by dynamic randomized single and double number grouping. The levels ofCK, LDtt, CKMB, the disappearance of clinical symptoms and the disappearance of signs were observed in 2 groups of patients treated with fructose diphosphate and astragalus respectively. Results The number of patients in the observation group was 70 cases, CK： （121.55 ± 30.41） IU/L, LDH： （150.24 ± 30.24） U/L, CKMB： （164.24 ± 15.24） IU/L, the time of disappearance of clinical symptoms was （16.24 ± 1.54） days, the disappearing time of the sign was （15.21 ± 1.11） days; Control group treatment effect was 55 cases, CK： （169.65 ± 30.66） IU/L, LDH： （188.66 ± 34.56） U/L, CKMB： （195.69 ± 16.87） IU/L, the time of disappearance of clinical symptoms was （25.36 ± 2.54） days, the disappearing time of the sign was （26.66 ± 3.33） days, two groups of patients were compared with each index, the difference was statistically significant （P 〈 0.05）. Conclusion Fructose diphosphate has a certain effect in the treatment of viral myocarditis in children.