胃铋镁四联疗法治疗幽门螺杆菌相关性消化性溃疡的临床效果评价

Clinical Efficacy of Bismuth and Magnesium Quadruple Therapy in the Treatment of Helicobacter Pylori Related Peptic Ulcer

目的观察与探究胃铋镁四联疗法治疗幽门螺杆菌相关性消化性溃疡的临床效果。方法选取2013年10月—2016年10月于本院就诊及治疗的60例幽门螺杆菌相关性消化性溃疡患者作为研究对象,按照随机数字表法分为两组,每组各有30例患者,对照组患者给予枸橼酸铋钾四联疗法治疗,观察组患者给予胃铋镁四联疗法治疗,对比并分析两组患者的效果。结果观察组患者的治疗总有效率(93.33%)与对照组患者(90.00%)相对比,组间差异无统计学意义(P>0.05),观察组患者的不良反应总发生率(3.33%)与对照组患者(20.00%)相对比,组间差异有统计学意义(P<0.05)。结论应用胃铋镁四联疗法治疗幽门螺杆菌相关性消化性溃疡患者的效果较好。

Objective To observe and explore the clinical effect of bismuth and magnesium quadruple therapy on Helicobacter pylori related peptic ulcer. Methods From October 2013 to October 2016, cases of Helicobacter pylori associated peptic ulcer patients as the research object, randomly divided into two groups, 30 patients in each group, the control group was treated with bismuth potassium citrate quadruple therapy, patients in the observation group were treated with bismuth magnesium quadruple therapy comparison and analysis the effect of two groups of patients. Results The total efficiency the observation group （93.33%） and control group （in 90% patients） were compared, no significant difference between the groups （P〉0.05）, the adverse reactions of patients with the total incidence rate （3.33%） and control group （20% patients） were compared, the differences between groups were statistically significant （P〈0.05）. Conclusion The combination of bismuth and magnesium is effective in the treatment of Helicobacter pylori associated peptic ulcer.