磁共振弥散加权成像对早产儿脑白质损伤的早期评价和诊断价值

The value of MR diffusion weighted imaging in early assessment and diagnosis of white matter damage in preterm infants

目的探讨磁共振弥散加权成像(DWI)对早产儿脑白质损伤的早期评价和诊断价值,为临床诊疗提供依据。方法选取2012年1月到2016年1月该院疑似脑白质损伤的早产儿69例,对所有患儿均行头颅B超和DWI检查,两种方法比较检查效果。结果 DWI确诊率为95.65%(66/69)显著高于B超的71.01%(49/69),两组比较差异具有统计学意义(P<0.05);DWI诊断早产儿脑白质损伤的特异度(95.34%)显著高于B超(81.32%),两组比较差异具有统计学意义(P<0.05)。结论DWI诊断早产儿脑白质损伤具有较高的确诊率,诊断的特异性也较高。

Objective To discuss the value of MR diffusion weighted imaging（DWI） in early assessment and diagnosis of white matter damage in preterm infants.Methods A total of 69 premature infants with suspected brain white matter injury in our hospital from January 2012 to January 2016 were selected,all the patients were examined by ultrasonography and DWI,and examination results were compared.Results The diagnosis rate of DWI was 95.65%（66/69）,which was significantly higher than that of B-mode ultrasonography[71.01%（49/69）],the difference was statistically significant（P〈0.05）.Specificity of DWI diagnosis of brain white matter damage in premature infants（95.34%） was significantly higher than B ultrasound（81.32%）,the difference was statistically significant（P〈0.05）.Conclusion DWI diagnosis of cerebral white matter damage in preterm infants has a high rate of diagnosis,which could improve the specificity of diagnosis.