广东省河源市连平县慢性阻塞性肺疾病调查分析

Investigation and Analysis of Chronic Obstructive Pulmonary Disease in Lianping County in Heyuan City in Guangdong Province

目的调查广东省河源市连平县≥20岁人群慢性阻塞性肺疾病的患病率，并分析其危险因素。方法整群随机抽取连平县4个自然村1909例20-85岁居民，进行问卷调查、肺功能及支气管扩张试验。结果资料完整1481人，慢性阻塞性肺疾病患病率10．9％（162／1481），男性患病率18．2％（136／746）高于女性3．5％（26／735），差异有统计学意义（P〈0．05）。男性、吸烟、低体重、儿童时期经常咳嗽是慢性阻塞性肺疾病的危险因素。结论连平地区慢性阻塞性肺疾病患病率较高，吸烟和儿童时期经常咳嗽是慢性阻塞性肺疾病患病的重要危险因素，需要加强戒烟工作，以及降低儿童时期咳嗽的发病率。

Objective To investigate the prevalence and to analyze risk factors of chronic obstructive pulmonary disease （COPD） among population of or over 20 years old in Lianping County in Heyuan City in Guangdong Province. Methods In the study, 1,909 subjects were invited by a cluster-randomized sampling for the population aged from 20 to 85 from four villages in Lianping County. There were all invited to investigation and spirometry tests including bronchodilatation test. Results There were 1,481 subjects with complete data of investigation and spirometric tests. The total prevalence of COPD was 10.9% （162/1,481）, and the prevalence of male subjects and female subjects was 18.2% （136/746） and 3.5% （26/735） respectively. The prevalence of male subjects was significantly higher than that of female subjects （P 〈 0.05）. Male subjects, smokers, adults with lower BMI and subjects with frequent coughing in childhood were more likely to be with COPD. Conclusion There is higher prevalence of COPD in Lianping County, and smoking and frequent coughing in childhood are important risk factors of COPD. Thus it is urgent to give up smoking and reduce coughing in children.