9-[4'-(吡啶-2-位)-(1,1'-联二苯-4-位)]-3,6-咔唑二硼酸的合成及表征

Synthesis and Characterization of 9-(4'-(pyridin-2-yl)-[1,1'-biphenyl]-4-yl) carbazole-3,6-diyl) diboronic acid

以咔唑和1,4-二溴苯为初始原料,经Ullmann反应、NBS亲电取代反应、Suzuki偶联和有机锂试剂法等反应,合成了9-[4'-(吡啶-2-位)-(1,1'-联二苯-4-位)]-3,6-咔唑二硼酸,并对影响反应的重要因素进行了考察和讨论。采用1H NMR,元素分析等方法对产品的纯度和结构进行了分析表征。

9 - （4＂- （ pyridin - 2 - yl） - [ 1,1 ＂- biphenyl ] - 4 - yl） carbazole - 3,6 - diyl） diboronic acid materials have been synthesized by Ullmann reaction, NBS electrophilie substitution, Suzuki cross -coupling reaction, Organic lithium reagent method using carbazole and 1,4 - dibromobenzene as the starting materials. The conditions which influence the reaction result were investigated and discussed. The purity and structure of the products were characterized by I H NMR, Elementary analysis , Mass soectrum.