儿童闭塞性细支气管炎的研究进展

Research advances of bronchiolitis obliterans in children

闭塞性细支气管炎在儿童中是一种相对少见而严重的慢性阻塞性肺疾病。以感染为最常见原因，主要临床特点是反复或持续咳嗽、气促、喘息，肺部有湿哕音和喘鸣音。目前诊断主要依赖临床表现、肺功能和高分辨率CT检查。目前尚无统一治疗标准，以经验治疗为主。该文主要对儿童闭塞性细支气管炎的辅助检查、诊断、治疗进行综述。

Bronchiolitis obliterans （BO） is a uncommon but severe chronic obstructive pulmonary disease in children. The infections are the most common causes in children. Its clinical manifestations are recurrent or persistent cough, shortness of breath, wheezing, crackles. The diagnosis relies on clinical manifestations, lung function and high-resolution CT. There is no standard treatment,but experiential therapy. The article reviews the progress on laboratory examinations, diagnosis and treatment of BO.