G蛋白偶联雌激素受体信号通路与肺脏疾病
摘要
雌激素不仅决定人类的第二性征，还能调节人体多系统重要脏器的病理生理功能。既往观点认为，雌激素主要通过其经典的雌激素受体α/β（ERα/β）传递其生物信息。近年来，随着对雌激素膜受体相关研究的开展，一种全新的G蛋白偶联雌激素受体（GPER）进入了人们的视线。该受体在体内生殖、内分泌、神经、免疫以及心血管等多个系统组织中广泛表达，参与调节其正常生理功能；并且在恶性肿瘤、心血管系统、免疫系统等疾病过程中同样起着重要作用。
出处
《中国呼吸与危重监护杂志》
CAS
CSCD
北大核心
2017年第3期304-308,共5页
Chinese Journal of Respiratory and Critical Care Medicine
基金
2015年政府资助省级临床医学优秀人才项目
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共引文献3
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