1%罗哌卡因应用于硬膜外麻醉下剖宫产手术的可行性研究

Feasibility study of 1% ropivacaine used for epidural anesthesia on cesarean section

目的:以0.75%盐酸罗哌卡因注射液为对照,研究1%盐酸罗哌卡因注射液在剖宫产手术患者中实施硬膜外麻醉的可行性。方法:随机入组40例患者,均分为1%盐酸罗哌卡因注射液组(研究组,S)和0.75%盐酸罗哌卡因注射液组(对照组,C)。观察两组患者术前感觉阻滞上界达T6时间、感觉阻滞范围,术后感觉阻滞消失时间、手术医师满意度。结果:S组与C组比较,切皮时VAS的评分比较差异无统计学意义(P>0.05);S组的起效时间快于C组,镇痛的持续时间长于C组(P<0.05);与C组比较,S组的牵拉不适反应少、肌肉松弛的满意度高(P<0.05);研究药物对新生儿的脐动脉血PH值和Apgar评分的影响两组差异无统计学意义(P>0.05)。结论:1%盐酸罗哌卡因注射液应用于硬膜外麻醉下实施剖宫产术安全有效。

Objective Compared with 0. 7 5 % Ropivacaine Hydrochloride Injection, to investigate the feasibility of epidural anesthesia in 1% patients undergoing cesarean section with Ropivacaine Hydrochloride Injection. Method Forty patients were randomly divided into 1% ropivacaine hydrochloride injection group （study group,S） and 0. 7 5 % ropivacaine hydrochloride in-jection group （ control group , C ）. To observe the two groups of patients with preoperative sensory block upper bound of T6 , sensory block scope, the postoperative feeling disappear time block, the surgeon satisfaction. Results There was no significant difference in the score of VAS between the S group and the C group （P 〉0. 05） ; onset time of group S was faster than group C,duration of analgesia was longer than group C （ P 〈 0. 05 ） ; and group C compared with group S , the dragging pain reaction of the group S was less,muscle relaxation of satisfaction was higher （ P 〈0. 05 ） for the operation doctor;There was no significant difference between the two groups in the study of umbilical artery blood pH and Apgar score of neonates （ P 〉 0. 05 ）. Conclusion The 1 % Ropiva-caine Hydrochloride Injection used in epidural anesthesia is safe and effective of cesarean section.