滋阴养血-化痰祛瘀-补肾中药序贯治疗多囊卵巢综合征患者胰岛素抵抗的临床研究

Clinical study on sequential therapy of nourishing Yin, nourishing blood, resolving phlegm and removing blood stasis and tonifying kidney in treating PCOS of insulin resistance

目的探究滋阴养血-化痰祛瘀-补肾中药序贯治疗多囊卵巢综合征患者胰岛素抵抗的临床疗效。方法选取符合纳入标准的患者90例,按随机数字表法分为中药序贯治疗组、二甲双胍对照组、达英-35对照组,治疗周期为3个月经周期,于入组前、治疗后进行指标测量。结果治疗后中药序贯组、二甲双胍组体重指数、空腹胰岛素降低(p<0.05),二甲双胍组优于中药序贯组(p<0.05),达英-35组在治疗前后无显著性差异(p>0.05),中药序贯组优于达英-35组(p<0.05)。结论滋阴养血-化痰祛瘀-补肾中药序贯疗法可降低体重指数、空腹胰岛素,改善多囊卵巢综合征胰岛素抵抗。

Objective To study the clinical efficacy of nourishing Yin, nourishing blood, resolving phlegm and removing blood stasis and tonifying kidney herbs in the treatment of polycystic ovary syndrome patients with insulin resistance. Methods 90 patients were randomly divided into Traditional Chinese Medicine sequential therapy group, Metformin group and Diane-35 group. Treatment period is 3 months. Before and after treatment, the index was measured. Results The levels of BMI and FIN in Chinese medicine sequential group, and Metformin group became significantly lower than before, there were significant differences before and after treatment （p〈0.05）. Comparison of the three groups after treatment, the levels of BMI and FIN Metformin group BMI and FIN in Metformin group were lower than Traditional Chinese Medicine sequential group and Diane-35 group, Traditional Chinese Medicine sequential group were lower than Diane -35 group, the difference was statistically significant （p〈0.05）. Conclusion The Traditional Chinese Medicine sequential therapy of nourishing Yin, nourishing blood, resolving phlegm and removing blood stasis and tonifying kidney can reduce BMI and FIN and improve the insulin resistance of PCOS.