通阳活血颗粒对中风患者肢体运动功能的影响

The effects of TongYangHuoXue granule on the limb motor function of Ischemic stroke patients with Qi deficiency and blood stasis

目的观察通阳活血颗粒对气虚血瘀型中风患者肢体运动功能的影响。方法将47例证属气虚血瘀型缺血性中风患者随机分为治疗组(24例)、对照组(23例),治疗组予基础治疗+通阳活血颗粒,对照组单纯予基础治疗;分别于治疗前、治疗14天后采用缺血性中风证候要素诊断量表、美国国立卫生研究院卒中量表(National institutes of health stroke scale,NIHSS)、三重磁刺激技术(TST)评定患者中医症候要素、神经功能及皮质脊髓束修复情况。结果治疗前,2组患者NIHSS、TST test值比较均无明显差异(p>0.05);经14天治疗后,治疗组TST test差值较对照组高(p<0.05);治疗组NIHSS与TST test值呈正相关(p<0.05)。结论 (1)TST test可用于评估缺血性中风患者运动功能缺损程度;(2)通阳活血颗粒可促进气虚血瘀型缺血性中风患者皮质脊髓束的修复,改善肢体运动功能。

Objective To observe the effect of TongYangHuoXue granule on the limbmotor function with Qi deficiency and blood stasis. Methods 47 cases of ischemic stroke patients with Qi deficiency and blood stasis, which were admitted to the Foshan Hospital of TCM from Marth 2015 to December 2015,were randomly divided into treatment group （24 cases） and control group （23 cases）. According to the standard, NIHSS, TST was evaluated before treatment and after 14-day treatment. Results Before treatment the NIHSS and TSTest test results were correlated （_p〈0.05）; There were significant difference between the treatment group and the control group in TST test, the results showed positive correlation before and after treatment （_p〈0.05）. Conclusions ① TST could quantitatively evaluate the impairment of corticospinal tracts and reflect the neurical function of the Ischemic stroke patients.②TongYangHuoXue granule could improve the TST testand promote motor function of the ischemic stroke patients with Qi deficiency and blood stasis.