中老年人群饮茶与血脂水平关系的横断面研究

A Cross-sectional Study for the Relationship Between Tea Drinking and Blood Lipids in Middle and Aged Population

目的:既往研究表明,经常饮茶能降低心血管病风险并有利于血脂水平。我国人群中关于饮茶和血脂水平的关系研究较少。本研究旨在探索社区中老年人群中估计饮茶和血脂、脂蛋白水平的关系。方法:采用横断面研究方法,利用中国心血管病流行病学多中心协作研究队列2007年~2008年复查资料,纳入研究对象7 227人(男3 304人、女3 923人),平均年龄(55.6±7.1)岁。采用问卷调查收集饮茶资料。按性别分层,是否经常饮茶分组。采用协方差分析,评价是否经常饮茶与血脂、脂蛋白水平的关系。结果:调查人群中经常饮茶人数为3 012人(41.7%)。男性中经常饮茶1 946人(58.9%);女性中经常饮茶1 066人(27.2%)。协方差分析调整年龄、城乡、文化程度、吸烟、饮酒、腰围、每日红肉摄入量、工作体力劳动强度、运动强度、高血压病史、糖尿病史、高胆固醇血症病史后,男性中经常饮茶组与不经常饮茶组相比,血清低密度脂蛋白胆固醇(LDL-C)较低(差值:-0.12 mmol/L,P=0.0001),甘油三酯(TG)较高(差值:0.11 mmol/L,P=0.0001);女性中经常饮茶组高密度脂蛋白胆固醇(HDL-C)较高(差值:0.06 mmol/L,P<0.0001)。结论:中老年男性经常饮茶与血清LDL-C水平较低和TG水平较高相关;中老年女性经常饮茶与HDL-C较高相关,上述关系独立于可能的影响因素。社区人群长期规律饮茶对血脂、脂蛋白水平的作用还需进一步前瞻性研究证实。

Objective： Previous study indicated that tea drinking can reduce the risk of cardiovascular disease and be beneficial to blood lipids, while the relevant survey was few in Chinese population. Our research aimed to explore the relationship between tea drinking and blood lipids, lipoprotein levels in community based middle and aged population. Methods： A cross-sectional study was conducted based on the data cohort of ＂China multicenter collaborative study of cardiovascular epidemiology＂ in 2007-2008. A total of 7227 participants were enrolled including 3304 male and 3923 female at the mean age of （55.6±7.1） years. Tea drinking information was collected by questionnaire; participants were stratified by gender and grouped by regular tea drinking. Relationship between tea drinking and blood lipids, lipoprotein levels were assessed by covariance analysis. Results： There were 3012/7227 （41.7%） participants （male： 58.9% and female： 27.2%） regularly drunk tea. With adjusted age, urban and rural, education level, cigarette smoking, alcohol drinking, body mass index （BMI）, daily red meat intake, physical work intensity, exercise intensity, histories of hypertension, diabetes and hypercholesterolemia, in male gender, compared with non-regular tea drinker, regular tea drinker had decreased blood level of low density lipoprotein cholesterol （LDL-C）, the difference was -0.12 mmol/L, P=0.0001 and increased triglyceride （TG）, the difference was 0. 11 mmol/L, P=0.0001; in female gender, regular tea drinker showed increased high density lipoprotein cholesterol （HDL-C）, the difference was 0.06 mmol/L, P〈0.0001. Conclusion： In our research, regular tea drinking was negatively related to blood LDL-C level and positively related to TG in male gender, while it was positively related to HDL-C in female gender; the above correlations were independent from possible influencing factors. The impact of long term regular tea drinking on blood lipids and lipoprotein levels should be further prospectively investigated in community based middle and aged population.