摘要
散乱蛋白(Dvl)是广泛存在于人体组织内的一种蛋白,含有三个结构域:散乱蛋白轴蛋白(DIX)结构域、突触后密集区蛋白-95/大型肿瘤抑制基因/紧密连接跨膜蛋白(PDZ)结构域、散乱蛋白/Egl-10/普列克底物蛋白(DEP)结构域。散乱蛋白通过不同的结构域参与Wnt信号传导,影响神经系统发育与神经损伤后神经发生。
Dishevelled (Dvl) is a kind of protein widely existing in human tissue, containing three structural domains: Dishevelled and Axin (DIX); postsynaptic density protein-95, disc large tumour suppressor, zonula occludens-1 (PDZ); and Dishevelled, Egl-10 and pleck- strin (DEP). Dvl participates in the Wnt signaling through different structure domains to play a role in nervous system development and neurogenesis after nerve injury.
作者
王志敏
梅彩琴
WANG Zhi-min MEI Cai-qin(Qujing Medical College, Qujing, Yunnan 655000, Chin)
出处
《中国康复理论与实践》
CSCD
北大核心
2017年第5期548-552,共5页
Chinese Journal of Rehabilitation Theory and Practice