胺碘酮对充血性心力衰竭合并室性心律失常患者的效果观察

Effect of amiodarone on patients with congestive heart failure complicated with ventricular arrhythmia

目的研究并探讨对充血性心力衰竭合并室性心律失常患者实施胺碘酮治疗的临床效果。方法选取我院收治的100例充血性心力衰竭合并室性心律失常患者作为研究对象,采取数字随机表法将患者分为对照组和观察组,每组50例。对照组实施常规抗心衰治疗,观察组在对照组的基础上给予胺碘酮治疗。比较两组患者的临床总有效率,以及治疗前、后的LVEF、NT-pro BNP、6 min步行距离。结果观察组的临床总有效率为96.00%,明显高于对照组的80.00%(P<0.05)。治疗后,两组患者的LVEF、NT-pro BNP、6 min步行距离均较治疗前明显改善(P<0.05),且观察组明显优于对照组(P<0.05)。结论胺碘酮治疗充血性心力衰竭合并室性心律失常具有显著的临床疗效,可有效改善患者的心功能。

Objective To study and to explore the effect of amiodarone on patients with congestive heart failure complicated with ventricular arrhythmia. Methods One hundred cases of patients with congestive heart failure complicated with ventricular arrhythmia were selected as the study objects, and they were divided into control group and observation group according to the digital random table method, with 50 cases in each group. The control group was given routine heart failure treatment, while the observation group was given amiodarone on the basis of the control group. The clinical total effective rate, and the left ventricular ejection fraction （LVEF）, NT-proBNP, 6-minute walking distance of the two groups before and after treatment were compared. Results The total effective rate of the observation group was 96.00%, which was significantly higher than 80.00% of the control group （P〈0.05）. After treatment, the LVEF, NT-proBNP and 6- minute walking distance of the two groups were significantly improved （P〈0.05）, and the observation group was significantly better than those in the control group （P〈0.05）. Conclusion Amiodarone has significant clinical effect in the treatment of patients with congestive heart failure combined ventricular arrhythmia, which can effectively improve the cardiac function of patients.