显微镜结肠炎的诊疗进展

Diagnosis and treatment of microscopic colitis

显微镜结肠炎(microscopic colitis,MC)是一种以反复发作的、非出血性、分泌性水样腹泻为主要临床表现,结肠镜下结肠黏膜正常,病理显微镜下见特异性病理、组织学改变的一组临床、病理综合征,其主要包括淋巴细胞性结肠炎和胶原性结肠炎两种类型.近十余年来MC的发病率有所增高,相关研究愈来愈多,但临床医师对其认识有限.本文就收集到的国内、外的相关研究文献,对该病的流行病学、病因、临床症状、结肠镜诊断、病理学诊断及治疗方面的研究进展作一概述.

Microscopic colitis （MC） is a disorder clinically characterized by recurrent, non-hemorrhagic and secretory diarrhea. Colonoscopy often shows normal colonic mucosa, while pathological microscopy shows specific pathological and histological changes. MC includes two types： lymphocytic colitis and collagenous colitis. Over the past ten years, the incidence of MC has increased and there have been more and more studies on this condition; however, clinicians still have limited knowledge on this disease. In this paper, we will discuss the epidemiology, etiology, clinical symptoms, colonoscopic diagnosis, pathological diagnosis and treatment of MC.