强直性脊柱炎住院患者用药情况分析与评价

Medical Utilization Analysis and Evaluation of Hospitalized Patients with Ankylosing Spondylitis

目的:了解强直性脊柱炎住院患者的用药情况及发展趋势,为临床合理用药工作以及相关的医疗保险制度的改革提供参考。方法:以第一诊断及出院诊断是"强直性脊柱炎"为关键词,提取某医院2014年4月1日至2015年10月底1127份强直住院患者的电子病例及2014和2015年7-8月份382份强直住院患者的用药明细。采用金额排序法和频度分析法对医院强直住院患者的用药品种、用药特点、用药类型等方面进行回顾性分析。结果:(1)强直患者以年轻男性居多,且住院时间较长,严重影响其工作与生活,使生活质量下降。(2)强直住院患者用药涉及疾病本身的治疗用药以及针对其他受累器官和组织的辅助用药。(3)治疗用化学药品中柳氮磺吡啶、醋氯芬酸的使用率较高;治疗用中药以"中成药"为主;在辅助用化学药品中,抗骨质疏松用药和补充叶酸的使用较多。(4)生物制剂的治疗未被涉及。结论:强直性脊柱炎住院患者的治疗辅助用药所占比例较大,中西结合是该医院的治疗特点,中药花费总金额偏高,人均花费金额较高;治疗用化学药物使用频繁,人均花费金额较低。

Objective： To understand the medical utilization situation and developing trend of hospitalized patients with Ankylosing Spondylitis and to provide references for the reform of clinical rational drug use and relevant medical insurance system. Methods： Searched with the keyword ＂Ankylosing Spondylitis＂ in the first diagnosis and the discharge diagnosis, 1127 electronic medical records of hospitalized patients with Ankylosing Spondylitis from April 1, 2014 to the end of October, 2014 and 382 detailed data of the drug use from July-August 2014 and July-August 2015 were collected. Drug varieties, drug characteristics and drug categories were retrospectively analyzed by ranking the expense and the frequency. Results： Inpatients with Ankylosing Spondylitis were mostly young men and in the hospital for a long time, so their life quality was greatly degraded. The drugs of inpatients included therapeutic medication for disease itself and other auxiliary medication affecting organs and tissues. In terms of chemical drugs used in the treatment, Salazosulfapyridine and Aceclofenac was used frequently; the priority was given to the traditional Chinese medicine with ＂Chinese patent drugs＂; in adjuvant of chemical drugs,frequently and cost less. The use of biological agents is still limited in the hospital.