经皮神经电刺激联合苯甲酸利扎曲普坦治疗偏头痛的临床研究

A CLINICAL STUDY ON PERCUTANEOUS NERVE ELECTRICAL STIMULATION COMBINED WITH RIZATRIPTAN BENZOATE FOR MIGRAINE TREATMENT

目的:观察经皮神经电刺激联合苯甲酸利扎曲普坦治疗偏头痛的临床疗效。方法:将60例偏头痛患者采用数字表法随机分为苯甲酸利扎曲普坦药物治疗组(A组);经皮神经电刺激仪治疗组(B组);经皮神经电刺激联合苯甲酸利扎曲普坦治疗组(C组)。每组各20例。观察各组治疗后视觉模拟评分(visual analogue scale,VAS)和临床疗效的改善率。结果:C组治疗后VAS评分明显低于A组和B组,差异有统计学意义(P<0.05);C组治疗后疗效优于A组和B组(P<0.05),三组治疗期间无明显不良反应。结论:经皮神经电刺激联合苯甲酸利扎曲普坦药物治疗偏头痛疗效优于二者的单独治疗疗效。

Objective：The clinical effects were observed that migraine was treated by cutaneous nerve electrical stimulation and Rizatriptan Benzoate. Methods： Sixty patients with migraine were randomly divided into three groups： Rizatriptan Benzoate treatment （group A,n=20）; transcutaneous electrical nerve stimulator therapy （group B,n=20）; transcutaneous electrical nerve stimulation with Rizatriptan Benzoate treatment （group C,n=20）. The Visual Analogue Scale （VAS） and clinical curative effects were observed.Results： The VAS score in Group C after treatment was lower than that in group A and group B, the difference was statistically significant （P〈 0.05）; The curative effects in Group C showed significantly more improvment than that of group A and group B （P 〈 0.05）, there is no side effects in three groups during treatment.Conclusion：The combination of Rizatriptan Benzoate with transcutaneous electrical nerve stimulation in migraine is better than that of the separate treatment.