瑶医神火灸联合激素治疗多发性硬化

Yaoyi Shenhuo moxibustion combined with glucocorticoid in the treatment of multiple sclerosis

目的探讨瑶医神火灸联合激素治疗多发性硬化(multiple sclerosis,MS)的临床疗效及对生活质量的影响。方法将64例MS患者分为治疗组及对照组,治疗组采用瑶医神火灸+皮质激素治疗方法治疗3周,对照组采用皮质激素治疗,比较治疗前后两组临床疗效(EDSS评分),生活能力评定及生活质量。结果治疗组总有效率为90.62%,对照组总有效率为78.12%,经过比较总有效率差异具有统计学意义(P<0.05),在EDSS评分、生活能力评定的改善方面治疗组优于对照组(P<0.05),在治疗3周时更为明显。在生活质量方面,治疗组治疗前后各项指标除认知功能外均有统计学意义差异(P<0.05),对照组治疗前后除认知功能、疼痛外差异(P<0.05),治疗组与对照组治疗后比较,在躯体功能、躯体致角色受限、情绪状况、疼痛方面比较均有统计学意义差异(P<0.05)。结论瑶医神火灸联合激素治疗有利于提高MS患者临床疗效,提高日常生活能力,改善生活质量,特别是在改善躯体功能、情绪、疼痛方面具有优势。

Objective To observe the clinical efficacy of Yaoyi Shenhuo moxibustion combined with glucocorticoid on multiple sclerosis and the affect of quality of life. Methods 64 MS patients were randomly divided into observation group and control group. Patients in the observation group were treated with Yaoyi Shenhuo moxibustion combined with glucocorticoid while patients in the control group were treated with glucocorticoid. After treated for three weeks, the clinical efficacy （EDSS score）, life ability assessment and quality of life of the two groups were compared. Results The total effective rate of the treatment group was 90.62%, the total effective rate of the control group was 78.12%, and the total effective rate was significantly different （ P 〉0.05 ） , the EDSS score, ADL Barthel and quality of life in the observation group was better than the control group （ P〈0.05 ） , significantly in the third week. On quality of life, every function in the observation group except cognitive function was significantly better after treatment （ P 〉0.05 ） ; In the control group every function in the observation group except cognitive function and body pain was significantly better after treatment. Compared with control group, patients in the observation group were significantly better onphysical function, body role restriction, emotional function and body pain after treatment, Conclusion Yaoyi Shenhuo moxibustion combined with glucocorticoid can improve the clinical efficacy, the ability of daily living and quality of life of patients with MS, especially in the improvement of physical function, mood and pain.