奈达铂药物利用评价标准的建立与分析

Establishment of the criteria of nedaplatin for drug use evaluation

目的建立奈达铂药物利用评价（DUE）标准，为奈达铂的医嘱审核提供工具，为应用评价提供新方法。方法以奈达铂药品说明书等为前提，参考《抗肿瘤药物处方点评指南》、卫生部《抗肿瘤药物临床应用指导原则（征求意见稿）》、《肿瘤化学治疗药物使用规范》和奈达铂临床应用相关文献，分别从有效性、安全性、依从性、经济性4个部分确立奈达铂DUE标准的草稿，征询我院药事管理与药物治疗学委员会等专家意见，对DUE标准完成修订和完善。结果在有效性、安全性、依从性、经济性方面，建立了较为全面的奈达铂DUE标准。结论奈达铂DUE标准为相关医疗机构进行奈达铂临床廊用合王早忡评价槔供了方法。

Objective To establish of the criteria of nedaplatin for drug use evaluation （ DUE）, and provide new evidence for prescription evaluation. Methods Based on the instruction of nedaplatin, as well as the Guideline of Prescription Review for Antitumor Agents, the Principles of Clinical Application of Antitumor Agents （Draft） by Ministry of Health, the Standards of Drug Use for Chemotherapy and relevant literatures about clinical use of nedaplatin, a standard draft about nedaplatin DUE was established which focused on effectiveness, safety, compliance and drug economy. Then, experts from the Pharmacy Management and Pharmacotherapeutics Committee of our hospital were consulted. Results Comprehensive standards of nadaplatin DUE were established from the aspects of effectiveness, safety, compliance and drug economy. Conclusion The established standards of nedaplatin DUE can provide new approaches for rational evalu- ation in medical institutions.