肠外营养中氨基酸对新生儿临床结局的影响分析

Analysis of effect of amino acids in parenteral nutrition on neonatal clinical outcomes

目的分析肠外营养中氨基酸对新生儿临床结局的影响。方法 100例新生儿随机分成对照组和实验组,各50例。对照组新生儿选择常规护理,实验组新生儿在常规护理的同时,加强肠外营养(主要提供氨基酸),对两组新生儿的临床结局进行观察比较。结果实验组新生儿的机械通气时间和住院时间分别为(2.1±1.3)、(6.4±0.6)d;短于对照组(3.3±1.0)、(7.2±1.5)d,差异有统计学意义(P<0.05)。实验组新生儿并发症发生率为10.0%显著低于对照组的26.0%,差异有统计学意义(P<0.05)。结论肠外营养中氨基酸能有效改善新生儿的临床结局,让新生儿的机械通气时间和住院时间显著缩短,让并发症发生率有效降低,具有临床应用和推广价值。

Objective To analyze the effect of amino acids in parenteral nutrition on neonatal clinical outcomes. Methods A total of 100 newborns were randomly divided into control group and experimental group, with 50 cases in each group. The control group received conventional nursing, and the experimental group received strengthened parenteral nutrition （mainly providing amino acids） at the same time of conventional nursing. Clinical outcomes was observed and compared in two groups. Results The experimental group had duration of mechanical ventilation and hospitalization time respectively as （2.1 ± 1.3） and （6.4 ± 0.6） d, which were shorter than （3.3 ± 1.0） and （7.2 ±1.5） d in the control group, and their difference had statistical significance （P〈0.05）. The experimental group had significantly lower incidence of neonatal complications as 10.0% than 26.0% in the control group, and the difference had statistical significance （P〈0.05）. Conclusion Amino acids in parenteral nutrition can effectively improve clinical outcomes of newborns, significantly shorten duration of mechanical ventilation and hospitalization time in newborns and effectively reduce incidence of complications. So if has clinical application and promotion value.