中医四联疗法方案对溃疡性结肠炎的影响

Effect of Traditional Chinese Medicine Quadruple Therapy on Ulcerative Colitis

目的比较中医"四联疗法"治疗方案与单纯中药组及单纯西药组治疗溃疡性结肠炎的疗效差异。方法将脾虚湿热型溃疡性结肠炎患者120例,随机分为中医四联疗法组、中药组、西药组,每组各40例。每组均治疗30 d及停药3个月后观察临床疗效和肠镜表现积分、T细胞亚群、粪便钙卫蛋白等指标。结果中医四联疗法组在治疗30 d及停药3个月后临床疗效和肠镜表现积分、T细胞亚群、粪便钙卫蛋白等各项指标均优于中药组和西药组,差异有统计学意义(P<0.05),但中药组和西药组在各项指标上比较差异无统计学意义(P>0.05)。结论中医四联疗法可有效治疗溃疡性结肠炎,是值得推广的一种效高价廉的方法。

Objective To compare the curative effect of traditional Chinese medicine quadruple therapy, Chinese herbal medicine and Western medicine in the treatment of ulcerative colitis. Methods 120 eases of patients with dampness-heat due to spleen deficiency ulcerative colitis were randomly divided into traditional Chinese medicine quadruple therapy group, Chinese herbal medicine group and Western medicine group. Each group had 40 eases. After 30 days＇ treatment and withdrawal for 3 months, the clinical curative effect and colonoseopy integral, T cell subgroup, fecal calcium protein and other indicators were observed. Results After 30 days＇ treatment and withdrawal for 3 months, the curative effect and eolonoscopy integral, T eel] subsets and fecal calcium protein of tradi- tional Chinese medicine quadruple therapy group were superior to the Chinese herbal medicine group and Western medicine group, and there was statistical significance （P 〈 0.05） , but the indicators of the Chinese herbal medicine group and Western medicine group had no statistical significance （P 〉 0.05） . Conclusion The traditional Chinese medicine quadruple therapy can be effective in the treatment of ulcerative colitis, and is an effective method to promote with high price and low cost.