中西医联合治疗小儿肾病综合征的临床观察

Clinical Observation on Combined Traditional Chinese and Western Medicine in the Treatment of Infantile Nephrotic Syndrome

目的研究中西医联合治疗小儿肾病综合征的临床效果。方法将我院2015年2月—2016年6月小儿肾病综合征患儿100例随机分2组。西医组行西医治疗,中西医组行中西医联合治疗。比较2组患儿肾病综合征治疗效果;不良反应发生情况;治疗前和治疗后患儿24 h尿蛋白、血肌酐以及白蛋白的差异。结果中西医组患儿肾病综合征治疗效果高于西医组,P<0.05;中西医组不良反应发生情况无异于西医组,P>0.05;治疗前2组24 h尿蛋白、血肌酐以及白蛋白比较无显著差异,P>0.05;治疗后中西医组24 h尿蛋白、血肌酐以及白蛋白改善幅度更大,P<0.05。结论中西医联合治疗小儿肾病综合征的临床效果确切,可有效改善患儿症状以及肾功能,无严重副作用,具有良好的安全性和有效性,值得推广。

Objective To study the clinical effect of combined traditional Chinese medicine and Western medicine in the treatment of infantile nephrotic syndrome. Methods 100 cases of children with nephrotic syndrome in our hospital from February 2015 to June 2016 were randomly divided into two groups. The Western medicine group was treated with Western medicine. The integrated medicine group was given combined traditional Chinese medicine and Western medicine. The therapeutic effect, adverse reactions, urinary protein, serum creatinine and albumin difference of 24 hours were compared between the two groups. Results The therapeutic effect of the integrated medicine group was higher than that of the control group, P 〈 0.05. The oceurrence of adverse reactions between the integrated medicine group and the Western medicine group had no difference, P 〉 0.05. Before treatment, 24 hours urine protein, serum creatinine and albumin between the two groups had no significant difference, P 〉 0.05. After treatment, the 24 hours urine protein, seruin creatinine and albumin of the between improved more significantly P 〈 0.05. Conclusion The combined traditional Chinese medicine and Western medicine in the treatment of infantile uephrotie syndrome has definitely clinical effect, can effectively improve the symptoms and renal function, has no serious side effects, has good safety and effectiveness, and it is worth prorooting.