骨性关节炎致病因素的研究进展

Research Progress on the Etiological Factors of Osteoarthritis

骨关节炎是一种慢性进行性骨关节病,其主要病变是关节软骨的退行性改变伴有软骨下骨质硬化和继发性骨质增生。多见于中老年人。近几年来,随着年龄的增长和全社会人口老龄化进程加剧,本病的发病率明显增高,严重危害着中老年人的健康。但是由于本病病因病机复杂多样,现代医学对此也尚无确切的结论,导致临床上虽然治疗手段多样但缺乏针对性,本文就近几年相关文献提及到骨性关节炎的病因病机及致病因素做一综述,有利于更好地认识本病,以期为临床诊疗提供参考。

Osteoarthritis is a chronic and progressing osteoarthrosis, the main pathological changes involves the deterioration of cartilage accompanied with osteosclerosis of subchondral bone and secondary degeneration hyperplasia of the one under cartilage. This disease is the majority in old people. Recently, along with our country population aging advancement even more obvious, incidence of osteoarthritis has been increased rapidly, which seriously jeopardize their health. Because of the pathogenesis of complex and diversity, and the modem medicine has no definite conclusion about it; there are many treatments but absent of target, so that here is a summary about research progress on the etiological factors of osteoarthritis, and provides a clearer cognition for the clinical therapy.